4.7 Article

Self-assembled nanoparticles as multifunctional drugs for anti-microbial therapies

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 57, Pages 7649-7651

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00349g

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A self-assembled nanoparticle containing a photosensitizer and a Trojan-horse moiety (cholesterol), binds an anti-TB pro-drug and increases 1000-fold its activity against mycobacteria. These minimalist constructs will allow development of economically viable, efficient drug preparations for the treatment of drug-resistant TB infections.

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