Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 61, Pages 8312-8315Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00452c
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Funding
- Singapore National Research Foundation [R-279-000-390-281]
- SMART [R279-000-378-592]
- Institute of Materials Research and Engineering [IMRE/12-8P1103]
- Singapore Institute for Clinical Sciences (ASTAR)
- Research Grants Council of Hong Kong [IIKUST2/CRF/10, N HICUST620/11]
- Guangdong Innovative Research Team Program [201101C0105067115]
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We report the design and synthesis of a specific mitochondrial fluorescent probe AIE-MitoGreen-1 with AIE characteristics to monitor the mitochondrial morphology changes and identify the differentiation process of living brown adipose cells. The probe AIE-MitoGreen-1 has significant advantages such as high cellpermeability, good mitochondrial retention, low background fluorescence, large Stokes shift, and low toxicity.
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