Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 62, Pages 8518-8521Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03315a
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Funding
- National 973 Program [2011CB910403]
- NSFC [21235005]
- Shanghai Municipal Natural Science Foundation [12ZR1434900]
- Shanghai Key Laboratory of New Drug Design [11DZ2260600]
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Two fluorescent probes SPS1 and SPS2 were designed by connecting biotin to an environment-sensitive coumarin fluorophore. Streptavidin and avidin induced dramatical fluorescence changes in both probes. SPS2 has potential in fluorescent imaging of biotin receptor-enriched tumor cells.
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