4.7 Article

Temperature-responsive telechelic dipalmitoylglyceryl poly(N-isopropylacrylamide) vesicles: real-time morphology observation in aqueous suspension and in the presence of giant liposomes

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 61, Pages 8350-8352

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03199g

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Funding

  1. Japan Society for the Promotion of Science (JSPS) [25350549]
  2. Natural Sciences and Engineering Research Council of Canada (Discovery program)
  3. World Premier International Research Center Initiative (WPI) MEXT Japan
  4. Grants-in-Aid for Scientific Research [24570178, 24104004, 25610117, 22220001] Funding Source: KAKEN

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Telechelic alpha,omega-di(twin-tailed poly(N-isopropylacrylamides)) form polymersomes in water that increase in size by fusion when the water temperature exceeds the polymers cloud point temperature. Hybrid vesicles form in mixed suspensions of giant phospholipid liposomes and polymersomes by adsorption/fusion, and undergo further transformations, such as fission.

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