4.7 Article

Postsynthetic modification of an amino-tagged MOF using peptide coupling reagents: a comparative study

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 78, Pages 11472-11475

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02650k

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Funding

  1. Center for NanoScience Munich (CeNS)

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The suitability of four peptide coupling reagents for postsynthetic modification (PSM) of amino-tagged metal-organic frameworks (MOFs) with carboxylic acids was investigated. Mild reaction conditions at room temperature allow effective covalent attachment of drugs and biomolecules inside the pores of MOFs with moderate chemical stability.

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