4.7 Article

Simultaneous detection of mercury(II) and silver(I) ions with picomolar sensitivity

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 5, Pages 572-574

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46884d

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Funding

  1. National Natural Science Foundation of China [21325523]
  2. Award for the Hundred Talent Program of the Chinese Academy of Science

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We develop a new method for the simultaneous detection of Hg2+ and Ag+ by integrating bifunctional strand displacement amplification and multiplexed short linear quencher-fluorophore probes. This method exhibits excellent specificity and high picomolar sensitivity, which is improved by up to 4 orders of magnitude compared to the current approaches for metal ion assay.

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