Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 29, Pages 3795-3798Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48239a
Keywords
-
Categories
Funding
- National Institutes of Health [AI072443]
Ask authors/readers for more resources
Glutathione-complexed [2Fe-2S] cluster is shown to significantly stimulate the ATPase activity of an ABCB7-type transporter in both solution and proteoliposome-bound forms (K-D similar to 68 mu M). The cluster is a likely natural substrate for this transporter, which has been implicated in cytosolic Fe-S cluster protein maturation. A possible substrate-binding site is identified on a new structural model for the active transporter.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available