4.7 Article

Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 23, Pages 3010-3013

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00112e

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Lactosyl ceramide analogues carrying novel bifunctional BODIPY-based fluorescent tags were designed and synthesised for live cell imaging. Addition of azide functionality on the fluorophore facilitated isobaric tagging for quantitative multiplexed analysis of biomolecules based on tandem mass spectrometry.

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