Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 21, Pages 2784-2786Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49683j
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Funding
- National Science Foundation for Young Scientists of China [21202156]
- National Natural Science Foundation of China [21372210]
- Fundamental Research Funds for the Central Universities [WK2060190023]
- Natural Science Foundation of Anhui Province [1308085QB37]
- University Science and Technology of China (USTC)
- Singapore Ministry of Education Academic Research Fund [MOE2011-T2-1-013, MOE2010-T2-2-067]
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A cyclization reaction between enamides and alkynes catalyzed by palladium(II) acetate is described. In this method, the molecular oxygen serves as an efficient oxidant for the Pd(II)/Pd(0) catalytic cycle. The simple reaction conditions permit this methodology to be used as a general tool for the preparation of multi-substituted pyrroles.
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