Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 56, Pages 7538-7541Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02295e
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Funding
- National Natural Foundation of China [21272202, J1210042]
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The first highly enantioselective iso-Pictet-Spengler reaction of C-2-linked o-aminobenzylindoles with trifluoromethyl ketones was developed using chiral spirocyclic phosphoric acids as organocatalysts, which afforded optically active benzazepinoindoles bearing trifluoromethylated quaternary stereocenters.
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