Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 76, Pages 11147-11150Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03082f
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Funding
- MARVENE (ERA-NET NanoSci-E+ NAN092) EU project
- Engineering and Physical Sciences Research Council (EPSRC) UK [EP/H007040/1]
- Engineering and Physical Sciences Research Council [EP/H007040/1] Funding Source: researchfish
- EPSRC [EP/H007040/1] Funding Source: UKRI
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We report that Fe3O4 nanoparticles are able to catalyse lipid peroxidation in liposomes at acidic but not neutral pH. The oxidation is dependent on either pre-existing lipid peroxides or hydrogen peroxide as a substrate. This is the first evidence for metal oxide nanoparticles as peroxidase mimetics oxidising biomolecules in a relevant environment.
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