4.7 Article

Microglia specific fluorescent probes for live cell imaging

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 9, Pages 1089-1091

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45715j

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Funding

  1. Agency of Science and Technology, Singapore (A*STAR) Biomedical Research Council
  2. Singapore Ministry of Education Academic Research Fund Tier 2 [MOE2010-T2-2-030]

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Small molecule fluorescent probes offer significant advantages over conventional antibody and fluorescent protein labeling techniques. Here we present CDr10a and CDr10b, dyes that label live microglia specifically. They may be applied to the isolation and imaging of live microglia when investigating their role in neuroinflammatory diseases.

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