4.7 Article

Imaging in living cells using nu B-H Raman spectroscopy: monitoring COSAN uptake

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 25, Pages 3370-3372

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49658a

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Funding

  1. Generalitat de Catalunya [2009/SGR/00279]
  2. Spanish Ministerio de Ciencia e Innovacion [CTQ2010-16237]
  3. EPSRC grant [EP/I016260/1]
  4. MICINN
  5. EPSRC [EP/I016260/1] Funding Source: UKRI
  6. Engineering and Physical Sciences Research Council [EP/I016260/1] Funding Source: researchfish

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The boron-rich cobaltabisdicarbollide (COSAN) and its 8,8'-I-2 derivative (I2-COSAN), both of purely inorganic nature, are shown to accumulate within living cells, where they can be detected using nu B-H Raman microspectroscopy. This demonstrates an alternative method for cell labelling and detection.

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