4.7 Article

A multifunctional anomeric linker for the chemoenzymatic synthesis of complex oligosaccharides

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 54, Pages 7132-7135

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02222j

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Funding

  1. National Institute of General Medical Sciences [R01GM090269, P01GM107012]
  2. National Cancer Institute [F31CA180478]
  3. US National Institutes of Health
  4. NATIONAL CANCER INSTITUTE [F31CA180478] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM090269, P01GM107012] Funding Source: NIH RePORTER

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A new anomeric linker has been developed that facilitates the purification of glycans prepared by chemoenzymatic approaches and can readily give compounds that are appropriately modified for microarray development or glycan derivatives with a free reducing end that are needed as standards for the development of analytical protocols.

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