4.7 Article

Cationic amphiphilic non-hemolytic polyacrylates with superior antibacterial activity

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 53, Pages 7071-7074

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01583e

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Funding

  1. Center for Engineered Polymeric Materials, CUNY Graduate Center
  2. CUNY [RF 66617-0044]

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Acrylic copolymers with appropriate compositions of counits having cationic charge with 2-carbon and 6-carbon spacer arms can show superior antibacterial activities with concomitant very low hemolytic effect. These amphiphilic copolymers represent one of the most promising synthetic polymer antibacterial systems reported.

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