4.7 Article

Iridium-catalysed borylation of sterically hindered C(sp3)-H bonds: remarkable rate acceleration by a catalytic amount of potassium tert-butoxide

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 48, Pages 6333-6336

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01262c

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Funding

  1. MEXT [23105520]
  2. ACT-C FS from JST
  3. Grants-in-Aid for Scientific Research [25105728] Funding Source: KAKEN

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The C(sp(3))-H bonds located on the methyl groups of an isopropyl group participate in iridium-catalysed C-H borylation with bis-(pinacolato) diboron via a significant rate acceleration caused by a catalytic amount of t-BuOK.

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