Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 69, Pages 9835-9838Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02147a
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Funding
- MIUR (Italian Ministry for Research and University) grants FIRB MERIT [RBNE08HWLZ_001, 2010M2JARJ]
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A new Cu(I) probe (OBEP-CS1), bearing an alkyl-pyridinium moiety to get complete water solubility, was synthesized. Fluorescence titrations support copper binding and high selectivity in a water solution whereas formation of aggregates was excluded by DOSY experiments. The detection capability for intracellular Cu(I), especially localized in mitochondria, was demonstrated in differentiated neuroblastoma cells by confocal microscopy.
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