4.7 Article

Tripodal molecules for the promotion of phosphoester hydrolysis

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 47, Pages 6217-6220

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc00333k

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Funding

  1. Defence Science and Technology Laboratory through the Centre for Defence Enterprise scheme (JRH)
  2. ESPRC
  3. Dstl
  4. Royal Society
  5. Wolfson Foundation

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A series of low molecular weight tripodal amide/histidine-containing compounds (1-2) have been synthesised and shown to increase the rate of bis-(p-nitrophenyl) phosphate (BNPP) and soman (GD) breakdown in buffered aqueous solution.

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