4.7 Article

Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 15, Pages 1851-1853

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48761j

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Funding

  1. Max Planck Society
  2. Minerva Stiftung (post-doctoral Minerva fellowship)
  3. European Research Council (ERC Advanced Grant AUTOHEPARIN)

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Current strategies for the synthesis of glycopeptides require multiple manual synthetic steps. Here, we describe a synthesis concept that merges solid phase peptide and oligosaccharide syntheses and can be executed automatically using a single instrument.

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