4.7 Article

A rhodamine-appended water-soluble conjugated polymer: an efficient ratiometric fluorescence sensing platform for intracellular metal-ion probing

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 16, Pages 2040-2042

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc48649d

Keywords

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Funding

  1. National Key Scientific Program of China [2011CB911000]
  2. NSFC [21325520, 21327009, 21221003, J1210040, 21177036, 21135001]
  3. National Instrumentation Program [2011YQ030124]
  4. Ministry of Education of China [20100161110011]
  5. Hunan Provincial Natural Science Foundation [11JJ1002]

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The water-soluble CP was conjugated with a rhodamine spirolactam for the first time to develop a new FRET-based ratiometric fluorescence sensing platform (CP 1) for intracellular metal-ion probing. CP 1 exhibits excellent water-solubility with two well-resolved emission peaks, which benefit ratiometric intracellular imaging applications.

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