Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 79, Pages 8982-8984Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc43685c
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Funding
- National Nature Science Foundation of China [21272222, 21172205, 20972144, 20932002, 91213303, J1030412]
- Ministry of Science and Technology of China [2010CB912103]
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The direct oxidative synthesis of alpha-ketoamides via anodic oxidation was developed by using dioxygen as a reactant under mild conditions. This methodology has a broad substrate scope (aromatic amines, aliphatic amines and ammonium acetate) and opens up an interesting and attractive avenue for the synthesis of alpha-ketoamide derivatives.
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