Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 45, Pages 5162-5164Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc41479e
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Funding
- National Natural Sciences Foundation of China [21235006]
- Creative Research Group Project of NSFC [21021004]
- China State Key Basic Research Program Grant [2013CB-911203, 2012CB910601, 2012CB-910101]
- Analytical Method Innovation Program of MOST [2009IM031800, 2010IM030500]
- Knowledge Innovation program of DICP
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Silica-carbon composite nanoparticles (NP-MCM-C) with uniform shapes and highly ordered mesoporous structures are directly prepared by using template polymers as the carbon source. And, taking advantage of the size exclusion effect of the mesopores to proteins and the specific interaction between carbon and oligosaccharides, the prepared nanoparticles are utilized to enrich N-linked glycans from complex biological samples with high selectivity and efficiency.
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