4.7 Article

Unprecedented ortho-acylation of azoxybenzenes with alpha-oxocarboxylic acids by Pd-catalyzed C-H activation and decarboxylation

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 80, Pages 9170-9172

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45492d

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Funding

  1. National Science Foundation of China [21172092]
  2. Department of Education, Anhui Province [KJ2013B246]

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A palladium-catalyzed ortho-acylation reaction of azoxybenzenes with alpha-oxocarboxylic acids was developed in the presence of K2S2O8. The established methodology provides a direct approach to obtain acylated azoxybenzenes in good yields.

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