Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 99, Pages 11588-11619Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47368f
Keywords
-
Categories
Funding
- NIH [GM071779]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1048804] Funding Source: National Science Foundation
Ask authors/readers for more resources
In nucleophilic phosphine catalysis, tertiary phosphines undergo conjugate additions to activated carbon-carbon multiple bonds to form beta-phosphonium enolates, beta-phosphonium dienolates, beta-phosphonium enoates, and vinyl phosphonium ylides as intermediates. When these reactive zwitterionic species react with nucleophiles and electrophiles, they may generate carbo-and heterocycles with multifarious molecular architectures. This article describes the reactivities of these phosphonium zwitterions, the applications of phosphine catalysis in the syntheses of biologically active compounds and natural products, and recent developments in the enantioselective phosphine catalysis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available