Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 84, Pages 9854-9856Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46111d
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Funding
- NSFC [21072044]
- [NCET-11-0938]
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Highly enantioselective phase-transfer alkylation of 3-substituted-2-oxindoles with activated bromomethanes is disclosed with a broad substrate scope by using bicyclic guanidinium as a catalyst and a Lewis acid as the co-catalyst. The alkylation adducts are versatile intermediates to accomplish the syntheses of pyrroloindolines and furoindolines.
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