4.7 Article

Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 40, Pages 4510-4512

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc39020a

Keywords

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Funding

  1. National Natural Science Foundation of China [31200576, 81072576, 91027033]
  2. Chinese Academy of Sciences [KJCX2-EW-N06-01]

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A G-quadruplex is identified which can exhibit two different motifs, respectively, corresponding to Na+ and K+. The relative amount of each motif is related to the Na+/K+ ratio. Based on selective recognition of the G-quadruplex motifs by a cyanine dye aggregate, a method for both colorimetric and quantitative measurements of Na+/K+ ratios is constructed.

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