4.7 Article

Highly efficient transformation of levulinic acid into pyrrolidinones by iridium catalysed transfer hydrogenation

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 47, Pages 5408-5410

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc41661e

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Funding

  1. National Science Foundation of China [21103102]
  2. Program for Changjiang Scholars and Innovative Research Team in University [IRT 1070]
  3. Cheung Kong Scholar Programme
  4. Fundamental Research Funds for the Central Universities [GK200902009]
  5. Shaanxi Normal University [S2011YB02]

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Levulinic acid (LA) is transformed into pyrrolidinones via iridium-catalysed reductive amination using formic acid as the hydrogen source under aqueous conditions. The catalytic system is the most active and performs under the mildest conditions ever reported for the reductive amination of LA.

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