Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 79, Pages 9033-9035Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45216f
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Funding
- National Natural Science Foundation of China [21272093]
- Research Fund for the Doctoral Program of Higher Education of China [20120061120117]
- State Key Laboratory of Supramolecular Structure and Materials
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Mesoporous silica nanoparticles (MSNs) have been surface-functionalized with choline moieties encircled by sulfonatocalix[4]arenes. Two enzyme cleavable sites are incorporated in the stalks for specific enzymes to regulate the release of loaded cargos from MSNs. These gated materials show a clear enzymatic response and proven orthogonality.
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