4.7 Article

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(IV) phthalocyanine as an activatable photosensitiser

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 39, Pages 4274-4276

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37251g

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Funding

  1. Research Grant Council of the Hong Kong Special Administrative Region [402211]

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A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.

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