Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 83, Pages 9570-9572Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45487h
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Funding
- Natural Science Foundation of China [21101028]
- Major Project of the State Ministry of Science and Technology of China [2011ZX09101-001-04]
- Natural Science Foundation of Fujian Province [2012J05021]
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In this study, two phthalocyanine-erlotinib conjugates linked by an oligoethylene glycol chain have been synthesised and fully characterised. Having erlotinib as the targeting moiety, the two conjugates exhibited high specific affinity to HepG2 cancer cells and tumour tissues, therefore leading to high photodynamic activity.
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