Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 14, Pages 1401-1403Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc38349g
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Funding
- National Natural Foundation of China [21272202]
- Fundamental Research Funds for the Central Universities
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The first catalytic asymmetric pseudo five-component (AB(2)C(2) type) reaction is reported. A spirocyclic chiral phosphoric acid catalyzed one-pot multicomponent reaction of aromatic aldehydes, anilines and beta-ketoesters and afforded highly functionalized enantioenriched tetrahydropyridines with high levels of stereocontrol.
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