Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 26, Pages 2712-2714Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36808k
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Funding
- TCU RCAF
- Robert A. Welch Foundation [P-1760]
- NIH [P01 AG022550, P01 AGAG027956]
- NIH training grant [T32 AG020494]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [U54GM104942] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [P01AG022550, T32AG020494, P01AG027956] Funding Source: NIH RePORTER
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Metal-ion misregulation and oxidative stress have been linked to the progressive neurological decline associated with multiple neurodegenerative disorders. Transition metal-mediated oxidation of biomolecules via Fenton chemical reactions plays a role in disease progression. Herein we report the synthesis, characterization and antioxidant activity of 2; a pyclen derivative with enhanced antioxidant character.
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