Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 82, Pages 9458-9460Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc43985b
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Funding
- Chinese Academy of Sciences
- National Basic Research Program of China (973 Program) [2011CB911002]
- National Natural Science Foundation of China [21075119, 91027036, 21275139]
- Pillar Program of Changchun Municipal Bureau of Science and Technology [2011225]
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A new approach for the sensitive and selective sensing of a protein has been developed. Cytochrome c could quench the fluorescence of a fluorophore labeled aptamer efficiently. The specific binding between the aptamer and the target protein resulted in a turn-on emission signal, which could be used for protein quantification.
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