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MOLECULAR PHARMACEUTICS (2011)
Visualising gold inside tumour cells following treatment with an antitumour gold(I) complex
Louise E. Wedlock et al.
METALLOMICS (2011)
THE ANTIMALARIAL FERROQUINE: FROM BENCH TO CLINIC
C. Biot et al.
PARASITE (2011)
Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links
Debadeep Bhattacharyya et al.
PLOS ONE (2011)
The intracellular redox stress caused by hexavalent chromium is selective for proteins that have key roles in cell survival and thiol redox control
Judith M. Myers et al.
TOXICOLOGY (2011)
Luminescent cyclometalated platinum(II) complexes containing N-heterocyclic carbene ligands with potent in vitro and in vivo anti-cancer properties accumulate in cytoplasmic structures of cancer cells
Raymond Wai-Yin Sun et al.
CHEMICAL SCIENCE (2011)
Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex
Steve D. Shnyder et al.
MEDCHEMCOMM (2011)
Contribution of [64Cu]-ATSM PET in molecular imaging of tumour hypoxia compared to classical [18F]-MISO - a selected review
Mickael Bourgeois et al.
NUCLEAR MEDICINE REVIEW (2011)
Crystal Structure of a Cisplatin-(1,3-GTG) Cross-Link within DNA Polymerase eta
Thomas Reissner et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Iridium Complex with Antiangiogenic Properties
Alexander Wilbuer et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
A Potent Trans-Diimine Platinum Anticancer Complex Photoactivated by Visible Light
Nicola J. Farrer et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Synthesis, Characterization and Anticancer Activity of Porphyrin-Containing Organometallic Cubes
Nicolas P. E. Barry et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2010)
Insulin Mimetic Effect of Tungsten Compounds on Isolated Rat Adipocytes
Aleksandra Topic et al.
BIOLOGICAL TRACE ELEMENT RESEARCH (2010)
Gold(I) complex of N,N '-disubstituted cyclic thiourea with in vitro and in vivo anticancer properties-potent tight-binding inhibition of thioredoxin reductase
Kun Yan et al.
CHEMICAL COMMUNICATIONS (2010)
Excursions in polynuclear platinum DNA binding
John B. Mangrum et al.
CHEMICAL COMMUNICATIONS (2010)
Photocytotoxic trans-Diam(m)ine Platinum(IV) Diazido Complexes More Potent than Their cis Isomers
Nicola J. Farrer et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Consequences of Cisplatin Binding on Nucleosome Structure and Dynamics
Ryan C. Todd et al.
CHEMISTRY & BIOLOGY (2010)
A Rigid Dinuclear Ruthenium(II) Complex as an Efficient Photoactive Agent for Bridging Two Guanine Bases of a Duplex or Quadruplex Oligonucleotide
Stephane Rickling et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Chemo-Genetic Optimization of DNA Recognition by Metallodrugs using a Presenter-Protein Strategy
Jeremy M. Zimbron et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Synthesis, Structural Characterisation and Quadruplex DNA Binding Studies of a New Gold(III) Pyrazolylpyridine Complex
Kogularamanan Suntharalingam et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Evidence for Drug Release from a Metalla-Cage Delivery Vector Following Cellular Internalisation
Olivier Zava et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Stable Anticancer Gold(III)-Porphyrin Complexes: Effects of Porphyrin Structure
Raymond Wai-Yin Sun et al.
CHEMISTRY-A EUROPEAN JOURNAL (2010)
Sequential Cytarabine and α-Particle Immunotherapy with Bismuth-213-Lintuzumab (HuM195) for Acute Myeloid Leukemia
Todd L. Rosenblat et al.
CLINICAL CANCER RESEARCH (2010)
Anticancer activity of osmium metalla-rectangles
Nicolas P. E. Barry et al.
DALTON TRANSACTIONS (2010)
Discovery of a strongly apoptotic ruthenium complex through combinatorial coordination chemistry
Seann P. Mulcahy et al.
DALTON TRANSACTIONS (2010)
Chromium: celebrating 50 years as an essential element?
John B. Vincent
DALTON TRANSACTIONS (2010)
Anticancer activity of opened arene ruthenium metalla-assemblies
Nicolas P. E. Barry et al.
DALTON TRANSACTIONS (2010)
Osmium(II)-versus ruthenium(II)-arene carbohydrate-based anticancer compounds: similarities and differences
Muhammad Hanif et al.
DALTON TRANSACTIONS (2010)
Arene ruthenium complexes as anticancer agents
Georg Suess-Fink
DALTON TRANSACTIONS (2010)
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4
Jimson H. Y. Wong et al.
EMBO JOURNAL (2010)
Permanent Encapsulation or Host-Guest Behavior of Aromatic Molecules in Hexanuclear Arene Ruthenium Prisms
Julien Freudenreich et al.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2010)
Chromium(III) propionate complex supplementation improves carbohydrate metabolism in insulin-resistance rat model
Ewelina Krol et al.
FOOD AND CHEMICAL TOXICOLOGY (2010)
Noble metal targeting of thioredoxin reductase - covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin
Stefanie Prast-Nielsen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Two Metals Are Better than One: Investigations on the Interactions between Dinuclear Metal Complexes and Quadruplex DNA
Kogularamanan Suntharalingam et al.
INORGANIC CHEMISTRY (2010)
PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses
Noel G. Faux et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry
Michael Groessl et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2010)
Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77 Å resolution
Ryan C. Todd et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2010)
Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties
Riccardo Rubbiani et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Cytotoxicity, Hydrophobicity, Uptake, and Distribution of Osmium(II) Anticancer Complexes in Ovarian Cancer Cells
Sabine H. van Rijt et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Organometallic Osmium Arene Complexes with Potent Cancer Cell Cytotoxicity
Ying Fu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Development of nitrosyl ruthenium complex-loaded lipid carriers for topical administration: improvement in skin stability and in nitric oxide release by visible light irradiation
Franciane Marquele-Oliveira et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)
Effects of Chromium Histidinate on Renal Function, Oxidative Stress, and Heat-Shock Proteins in Fat-Fed and Streptozotocin-Treated Rats
Ayhan Dogukan et al.
JOURNAL OF RENAL NUTRITION (2010)
Differentiating quadruplexes: binding preferences of a luminescent dinuclear ruthenium(II) complex with four-stranded DNA structures
Tom Wilson et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil™) and potential of other CXCR4 antagonists as stem cell mobilizers
Erik De Clercq
PHARMACOLOGY & THERAPEUTICS (2010)
Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols
Didier Hamels et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
New Ways of Killing the Beast: Prospects for Inorganic-Organic Hybrid Nanomaterials as Antibacterial Agents
Julia E. Bandow et al.
CHEMBIOCHEM (2009)
Targeting proteins with metal complexes
Eric Meggers
CHEMICAL COMMUNICATIONS (2009)
Stabilization of G-Quadruplex DNA with Platinum(II) Schiff Base Complexes: Luminescent Probe and Down-Regulation of c-myc Oncogene Expression
Peng Wu et al.
CHEMISTRY-A EUROPEAN JOURNAL (2009)
Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities
Tetsuro Shimakami et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Effect of metal coordination on the interaction of substituted phenanthroline and pyridine ligands with quadruplex DNA
Julie E. Reed et al.
DALTON TRANSACTIONS (2009)
Interactions of ruthenium coordination cubes with DNA
Nicolas P. E. Barry et al.
DALTON TRANSACTIONS (2009)
Transport pathways for arsenic and selenium: A minireview
Barry R. Rosen et al.
ENVIRONMENT INTERNATIONAL (2009)
Host-Guest Chemistry in the Hexanuclear (Arene)ruthenium Metalla-Prismatic Cage [Ru6(p-cymene)6(tpt)2(dhnq)3]6+
Nicolas P. E. Barry et al.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2009)
Organometallic Osmium(II) Arene Anticancer Complexes Containing Picolinate Derivatives
Sabine H. van Rijt et al.
INORGANIC CHEMISTRY (2009)
Ruthenium(II) Arene Anticancer Complexes with Redox-Active Diamine Ligands
Tijana Bugarcic et al.
INORGANIC CHEMISTRY (2009)
Synthesis, Structural Characterization, and Quadruplex DNA Binding Studies of Platinum(II)-Terpyridine Complexes
Kogularamanan Suntharalingam et al.
INORGANIC CHEMISTRY (2009)
Structure-activity relationships of 4-N-substituted ferroquine analogues: Time to re-evaluate the mechanism of action of ferroquine
Christophe Biot et al.
JOURNAL OF ORGANOMETALLIC CHEMISTRY (2009)
Influence of Oxygenation on the Reactivity of Ruthenium-Thiolato Bonds in Arene Anticancer Complexes: Insights from XAS and DFT
Thamayanthy Sriskandakumar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads
Shanta Dhar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Decomposition pathways for the photoactivated anticancer complex cis,trans,cis-[Pt(N-3)(2)(OH)(2)(NH3)(2)]: insights from DFT calculations
Luca Salassa et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2009)
Synthesis and Structure Activity Relationship of Organometallic Steroidal Androgen Derivatives
Siden Top et al.
ORGANOMETALLICS (2009)
Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor
Alex N. Bullock et al.
PLOS ONE (2009)
Metal and ligand control of sulfenate reactivity: Arene ruthenium thiolato-mono-S-oxides
Holm Petzold et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
The Complex-in-a-Complex cations [(acac)(2)M subset of RU6(p-iPrC(6)H(4)Me)(6)(tpt)(2)(dhbq)(3)](6+): A Trojan horse for cancer cells
Bruno Therrien et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
X-ray structure and designed evolution of an artificial transfer hydrogenase
Marc Creus et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Sectroscopic study of stability and molecular species of 12-tungstophosphoric acid in aqueous solution
Ivanka Holclajtner-Antunovic et al.
CANADIAN JOURNAL OF CHEMISTRY (2008)
Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl) methane (tpm) manganese tricarbonyl complex
Johanna Niesel et al.
CHEMICAL COMMUNICATIONS (2008)
KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
Christian G. Hartinger et al.
CHEMISTRY & BIODIVERSITY (2008)
Similar biological activities of two isostructural ruthenium and osmium complexes
Jasna Maksimoska et al.
CHEMISTRY-A EUROPEAN JOURNAL (2008)
New uses for old drugs.: Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro:: Mechanistic and pharmacological implications
Anna Rosa Sannella et al.
FEBS LETTERS (2008)
Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study
Shamila S. Gunatilleke et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2008)
Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: New insights from X-ray diffraction and mass spectrometry studies
Angela Casini et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2008)
Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes
Jasna Maksimoska et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Mitochondria-targeted chemotherapeutics:: The rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols
James L. Hickey et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Investigation of the redox behavior of ferroquine, a new antimalarial
Natascha Chavain et al.
MOLECULAR PHARMACEUTICS (2008)
Ferroquine, an Ingenious Antimalarial Drug - Thoughts on the Mechanism of Action
Faustine Dubar et al.
MOLECULES (2008)
cis-diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent:: Uptake, structure, function, and prospects
Katherine S. Lovejoy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles
Shanta Dhar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mechanism of transcriptional stalling at cisplatin-damaged DNA
Gerke E. Damsma et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase
Aaron Alt et al.
SCIENCE (2007)
Tumor necrosis factor α as a new target for renal cell carcinoma:: Two sequential phase II trials of infliximab at standard and high dose
Michelle L. Harrison et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Phosphorylation events implicating p38 and PI3K mediate tungstate-effects in MIN6 beta cells
Sandra Piquer et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: Comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link
Yibing Wu et al.
BIOCHEMISTRY (2007)
Exploring biologically relevant chemical space with metal complexes
Eric Meggers
CURRENT OPINION IN CHEMICAL BIOLOGY (2007)
Exploring chemical space with organometallics: Ruthenium complexes as protein kinase inhibitors
Eric Meggers et al.
SYNLETT (2007)
Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity
Anna F. A. Peacock et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Ruthenium complexes can target determinants of tumour malignancy
A. Bergamo et al.
DALTON TRANSACTIONS (2007)
Photoactivatable Platinum Complexes
Patrick J. Bednarski et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2007)
The bioinorganic and medicinal chemistry of carboranes: from new drug discovery to molecular imaging and therapy
Andrea F. Armstrong et al.
DALTON TRANSACTIONS (2007)
Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles
Nial J. Wheate et al.
DALTON TRANSACTIONS (2007)
Synthesis of DNA-sequence-selective hairpin polyamide platinum complexes
Robin I. Taleb et al.
CHEMISTRY-A EUROPEAN JOURNAL (2007)
Osmium(II) and ruthenium(II) arene maltolato complexes: Rapid hydrolysis and nucleobase binding
Anna F. A. Peacock et al.
CHEMISTRY-A EUROPEAN JOURNAL (2007)
Cancer statistics, 2007
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2007)
Biocoordination chemistry of bismuth: Recent advances
Nan Yang et al.
COORDINATION CHEMISTRY REVIEWS (2007)
A third mode of DNA binding: Phosphate clamps by a polynuclear platinum complex
Seiji Komeda et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Configurationally restricted bismacrocyclic CXCR4 receptor antagonists
Gina C. Valks et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Insulin-sensitizing and cholesterol-lowering effects of chromium (D-Phenylalanine)3
Xiaoping Yang et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2006)
Cyclooctadiene Ru(II) complexes of thiophene-2-carboxaldehyde-derived thiosemicarbazones: synthesis, characterization and antiamoebic activity
Shailendra Singh et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2006)
Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions
AFA Peacock et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Metal-based antitumour drugs in the post genomic era
PJ Dyson et al.
DALTON TRANSACTIONS (2006)
Diversity in guanine-selective DNA binding modes for an organometallic ruthenium arene complex
Hong-Ke Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
2D NMR spectroscopic evidence for unprecedented interactions of cis-[Rh-2(dap)-(mu-O2CCH3)(2)(eta(1)-O2CCH3)(CH3OH)](O2CCH3) with a DNA oligonucleotide: Combination of intercalative and coordinative binding
Mijeong Kang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
The thiol-based redox networks of pathogens: Unexploited targets in the search for new drugs
Timo Jaeger et al.
BIOFACTORS (2006)
Anti-TNF-alpha antibody therapies in autoimmune diseases
Kokona Chatzantoni et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Interactions of antitumor metallodrugs with serum proteins: Advances in characterization using modern analytical methodology
Andrei R. Timerbaev et al.
CHEMICAL REVIEWS (2006)
Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex: Detection of a sulfenato intermediate
FY Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Therapeutic applications of carbon monoxide-releasing molecules
R Motterlini et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2005)
Study of etanercept, a tumor necrosis factor-alpha inhibitor, in recurrent ovarian cancer
S Madhusudan et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Modifications of DNA by platinum complexes - Relation to resistance of tumors to platinum antitumor drugs
V Brabec et al.
DRUG RESISTANCE UPDATES (2005)
Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity
Christophe Biot et al.
MOLECULAR PHARMACEUTICS (2005)
Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent
H Baruah et al.
BIOCHEMISTRY (2005)
Selective estrogen receptor modulators in the ruthenocene series.: Synthesis and biological behavior
P Pigeon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Characterization of the FKBP•Rapamycin•FRB ternary complex
LA Banaszynski et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
A newly synthetic chromium complex -: chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance
XP Yang et al.
FEBS LETTERS (2005)
Protein recognition of macrocycles: Binding of anti-HIV metallocyclams to lysozyme
TM Hunter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells
S Kapitza et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2005)
Synthesis and anti-amoebic activity of gold(I), ruthenium(II), and copper(II) complexes of metronidazole
F Athar et al.
CHEMISTRY & BIODIVERSITY (2005)
The search of DNA-intercalators as antitumoral drugs: what it worked and what did not work
R Martinez et al.
CURRENT MEDICINAL CHEMISTRY (2005)
The composition of Ehrlich's salvarsan: Resolution of a century-old debate
NC Lloyd et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure
A Hegmans et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Anti-viral cyclam macrocycles: rapid zinc uptake at physiological pH
SJ Paisey et al.
CHEMICAL COMMUNICATIONS (2004)
Functionalized cyclopentadienyl titanium organometallic compounds as new antitumor drugs
OR Allen et al.
ORGANOMETALLICS (2004)
The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer
G Jaouen et al.
CURRENT MEDICINAL CHEMISTRY (2004)
NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex
YB Wu et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Effect of sodium molybdate on the status of lipids, lipid peroxidation and antioxidant systems in alloxan-induced diabetic rats
SR Panneerselvam et al.
CLINICA CHIMICA ACTA (2004)
A highly flexible dinuclear ruthenium(II)-platinum(II) complex: Crystal structure and binding to 9-ethylguanine
K van der Schilden et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Triplex mediated delivery of a platinum complex to a specific DNA target site
SK Sharma et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2004)
Platinum-intercalator conjugates: From DNA-targeted cisplatin derivatives to adenine binding complexes as potential modulators of gene regulation
H Baruah et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2004)
Kinetics of aquation and anation of Ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts
F Wang et al.
CHEMISTRY-A EUROPEAN JOURNAL (2003)
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase:: Adduct affinity and drug resistance
R Rawat et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media
O Novakova et al.
BIOCHEMISTRY (2003)
Osmic acid revisited: factors that predict a favourable response
R Bessant et al.
RHEUMATOLOGY (2003)
Synthesis, characterization, and DNA binding properties of a series of Ru, Pt mixed-metal complexes
RL Williams et al.
INORGANIC CHEMISTRY (2003)
Multi-nuclear platinum complexes as anti-cancer drugs
NJ Wheate et al.
COORDINATION CHEMISTRY REVIEWS (2003)
Antianglogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers
L Morbidelli et al.
BRITISH JOURNAL OF CANCER (2003)
Reduced afflinity for isoniazid in the S315T mutant of Mycobacterium tuberculosis KatG is a key factor in antibiotic resistance
SW Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-Mer duplex
SJ Berners-Price et al.
CHEMISTRY-A EUROPEAN JOURNAL (2003)
Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: Novel recognition mechanisms
HM Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Metal carbonyls: A new class of pharmaceuticals
TR Johnson et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Tumor necrosis factor signaling
H Wajant et al.
CELL DEATH AND DIFFERENTIATION (2003)
Nitric oxide (NO) - Biogeneration, regulation, and relevence to human diseases
K Bian et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Structure and dynamics of metallomacrocycles:: Recognition of zinc xylyl-bicyclam by an HIV coreceptor
XY Liang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in dexamethasone-treated rats
DS Kim et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2002)
Organometallic ruthenium(II) diamine anticancer complexes: Arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts
HM Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A
A Vacca et al.
BRITISH JOURNAL OF CANCER (2002)
Kinetic and equilibria studies of the aquation of the trinuclear platinum phase 11 anticancer agent [{trans-PtCl(NH3)2}2{μ-trans-Pt(NH3)2(NH2(CH2)6NH2)2}]4+ (BBR3464)
MS Davies et al.
INORGANIC CHEMISTRY (2002)
Coligand tuning of the DNA binding properties of bioorganometallic (eta(6)-arene)ruthenium(II) complexes of the type [(eta(6)-arene) Ru(amino acid)(dppz)](n+) (dppz = dipyrido[3,2-a : 2 ',3 '-c] phenazine), n=1-3
A Frodl et al.
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS (2002)
Inhibition of cancer cell growth by ruthenium(II) arene complexes
RE Morris et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
2.4 Å crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex
B Spingler et al.
INORGANIC CHEMISTRY (2001)
Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA
LG Marzilli et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Competitive binding of bismuth to transferrin and albumin in aqueous solution and in blood plasma
HZ Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Zinc and copper bind to unique sites of histatin 5
J Grogan et al.
FEBS LETTERS (2001)
Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: Evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers
JW Cox et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
[Ru(eta(6)-p-cymene)Cl-2(pta)] (pta=1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane): a water soluble compound that exhibits pH dependent DNA binding providing selectivity for diseased cells
CS Allardyce et al.
CHEMICAL COMMUNICATIONS (2001)
On the mechanism of the antitumor activity of ferrocenium derivatives
D Osella et al.
INORGANICA CHIMICA ACTA (2000)
Clinical and pharmacological phase I study with accelerated titration design of a daily times five schedule of BBR3464, a novel cationic triplatinum complex
C Sessa et al.
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