4.7 Article

Enantioselective ring-opening of meso-epoxides by aromatic amines catalyzed by a homochiral metal-organic framework

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 84, Pages 9836-9838

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45988h

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Funding

  1. Welch Foundation [AX-1593, AX-1730]

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The enantioselective ring-opening of meso-epoxides by aromatic amines was achieved by using a new chiral metal-organic framework UTSA-32a. The corresponding alpha-hydroxyamines were obtained with good yields and ee values (up to 89% ee).

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