4.7 Article

Design of irreversible optical nanothermometers for thermal ablations

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 7, Pages 680-682

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37271a

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Funding

  1. NCI/NIH [R21CA149814]
  2. Washington University Molecular Imaging Center

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Nanothermometers composed from a gold nanorod core, temperature sensitive linker and fluorescent dye are reported. The nanothermometers have low fluorescence due to a self-quenching mechanism at temperatures below 50 degrees C and become highly fluorescence above 70 degrees C.

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