4.7 Article

Blue two-photon fluorescence metal cluster probe precisely marking cell nuclei of two cell lines

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 91, Pages 10724-10726

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46690f

Keywords

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Funding

  1. National Key Basic Research Program of China [2013CB932703, 2013CB933704]
  2. National Natural Science Foundation of China [31271072, 31070891, 31300827]

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A bifunctional peptide was designed to in situ reduce Cu ions and anchor a Cu cluster. The peptide-Cu cluster probe, mainly composed of Cu-14, emitted blue two-photon fluorescence under femtosecond laser excitation. Most important, the probe can specifically mark the nuclei of HeLa and A549 cells, respectively.

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