Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 85, Pages 10025-10027Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45000g
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Funding
- John R. Oishei Foundation
- Bruce Holm Catalyst Fund
- NIH [CA-173309]
- Roswell Park's NCI Support Grant [P30CA16056]
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The first examples of air-stable Co-II paraCEST MRI contrast agents are reported. Amide NH protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the bulk water resonance. One complex has multiple CEST peaks that may be useful for ratiometric mapping of pH.
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