Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 40, Pages 4552-4554Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc41331d
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Funding
- National Natural Science Foundation of China [21102080, 20972085]
- Tsinghua University Initiative Scientific Research Program [2011Z02150]
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The CuCl catalyzed direct trifluoromethylation of sp(2) C-H bonds has been realized, using the Togni reagent as the CF3 source. This reaction achieves the goal of regio-selectively converting C-H into C-CF3 with ecological and readily available starting materials.
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