Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 39, Pages 4352-4354Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37206a
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Funding
- NSF [CHE-1056568, CHE-0619339, CHE-0443618]
- Alfred P. Sloan Foundation
- Amgen
- Boehringer Ingelheim
- Boston University
- AstraZeneca
- American Chemical Society Division of Organic Chemistry
- DAAD RISE Worldwide program
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1056568] Funding Source: National Science Foundation
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Herein we report a one-pot deoxygenation protocol for primary and secondary alcohols developed via the combination of the Garegg-Samuelsson reaction, visible light-photoredox catalysis, and flow chemistry. This procedure is characterized by mild reaction conditions, easy-to-handle reactants and reagents, excellent functional group tolerance, and good yields.
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