4.7 Article

Ru(II)-catalyzed intermolecular C-H amidation of weakly coordinating ketones

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 50, Pages 5654-5656

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42613k

Keywords

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Funding

  1. National Basic Research Program of China (973 Program) [2009CB825300]
  2. National Science Foundation of China [21172006]
  3. PhD Programs Foundation of the Ministry of Education of China [20120001110013]

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An efficient Ru(II)-catalyzed intermolecular amidation of weakly coordinating ketones with sulfonyl azides via C-H bond activation is described. The reaction proceeds with high functional group tolerance, providing a novel approach to practical ketone-directed intermolecular C-N bond formation in the absence of an additional oxidant.

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