4.7 Article

Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 31, Pages 3242-3244

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc40392k

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Funding

  1. Grants-in-Aid for Scientific Research [21106001, 21106002] Funding Source: KAKEN

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Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain alpha-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.

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