4.7 Article

A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 80, Pages 9158-9160

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc43161d

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Funding

  1. CNRS
  2. UDS
  3. ECPM
  4. National Research Agency
  5. Region Alsace

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The functionalization of superparamagnetic iron oxide nanoparticles (SPION) with PEGylated PAMAM dendrons through a bisphosphonate tweezers yielded 15 and 30 nm dendritic nano-objects stable in physiological media and showing both renal and hepatobiliary elimination.

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