Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 77, Pages 8716-8718Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc44188a
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Funding
- National Basic Research Program of China [2010CB732402]
- National Scientific Foundation of China [21205100, 21075104]
- Natural Science Foundation of Fujian Province for Distinguished Young Scholars [2010 J06004]
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A pair of single-molecule photo-responsive DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity was designed and fabricated. Compared with other DNA nanomachines, our DNA nanoscissors have the advantages of a clean switching mechanism, as well as robust and highly reversible operation.
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