4.7 Article

Cadmium-free quantum dots as time-gated bioimaging probes in highly-autofluorescent human breast cancer cells

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 6, Pages 624-626

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37529j

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Funding

  1. NIH COBRE [P30 GM103450-03]
  2. Arkansas Biosciences Institute

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We report cadmium-free, biocompatible (Zn)CuInS2 quantum dots with long fluorescence lifetimes as superior bioimaging probes using time-gated detection to suppress cell autofluorescence and improve the signal : background ratio by an order of magnitude. These results will be important for developing non-toxic fluorescence imaging probes for ultrasensitive biomedical diagnostics.

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