4.7 Article

A novel hydrazino-substituted naphthalimide-based fluorogenic probe for tert-butoxy radicals

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 56, Pages 6295-6297

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42052c

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Funding

  1. Program for New Century Excellent Talents in University [NCET-11-0306]
  2. Shandong Natural Science Foundation [JQ201019]
  3. Independent Innovation Foundation of Shandong University, IIFSDU [2010JQ005]

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A novel fluorogenic probe for tert-butoxy radicals based on the hydrazino-naphthalimide system is reported. Interestingly, different regioisomers exhibited significantly different optical properties toward ROS, which suggested 4-hydrazinyl naphthalimide as a potential new platform for the in vitro and in cellulo detection of alkoxyl radicals.

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