4.7 Article

Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 85, Pages 9980-9982

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc42250j

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Funding

  1. Hong Kong University Grants Committee Area of Excellence Scheme [AoE/P-03-08]
  2. City University of Hong Kong [9667061]

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A seriesofosmium(VI) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anticancer activities. These results establish that Os-VI RN is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

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