4.7 Article

Nickel-catalysed novel β,γ-unsaturated nitrile synthesis

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 24, Pages 2442-2444

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc00029j

Keywords

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Funding

  1. 973 Program [2012CB725302]
  2. National Natural Science Foundation of China [21025206, 21272180]
  3. China Postdoctoral Science Foundation [2012M521458]
  4. Program for Changjiang Scholars and Innovative Research Team in University [IRT1030]

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Through a nickel-catalysed Heck-type reaction, a direct coupling of alkenes with alpha-cyano alkyl bromides was achieved. This procedure provides a novel way for the synthesis of beta,gamma-unsaturated nitriles.

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