Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 98, Pages 11476-11478Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46166a
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Funding
- National Research Foundation of Korea (NRF)
- Korea government (MEST) [2012R1A2A4A01007108]
- Converging Research Center Program of the Ministry of Education, Science and Technology, Korea [2011K000864]
- National Research Foundation of Korea [2012R1A2A4A01007108] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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We engineered phototherapeutic sub-12 nm-sized polymeric micelles to treat malignant brain tumours (MBTs). The engineered nanoparticles in MBT cells enhanced the photocytotoxic efficiency more than 2.5-fold compared with parental and PEGylated photosensitisers (PSs). Increased subcellular co-localisation of PSs in mitochondria was observed.
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