4.7 Article

Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 85, Pages 9929-9931

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc44471f

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Funding

  1. JSPS KAKENHI [24550197]
  2. Grants-in-Aid for Scientific Research [13J03617, 24550197] Funding Source: KAKEN

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A metal-based fluorescent probe for H2O2, named MBFh2, releases a highly fluorescent resorufin in the seconds time scale even in the presence of 5 mu M H2O2. The use of MBFh2 enabled the visualization of intracellular H2O2 that was generated after stimulation of the epidermal growth factor.

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